Which bacteria produces the most heat-resistant spore?Ĭlostridium botulinum is the most heat-resistant pathogenic bacterium, and its spores are also among the most pressure-resistant microorganisms known. The endospore makes it difficult to kill bacteria. The calcium cross-links contribute to the heat resistance of the bacterium making for a hard barrier to penetrate. Once favorable conditions return, the protective proteins dissolve the spore coating and the vegetative cell functions resume Why are spores so difficult to destroy?ĭPA has the ability to cross-link with calcium that is embedded within the spore coat. Bacterial spores are extremely durable and can be very difficult to destroy even under extreme temperatures.
